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Conf Proc IEEE Eng Med Biol Soc · Jan 2004
Physiologically-based minimal model of agitation-sedation dynamics.
- A D Rudge, J G Chase, G M Shaw, and D Lee.
- Dept. of Mechanical Eng., Canterbury Univ., Christchurch, New Zealand.
- Conf Proc IEEE Eng Med Biol Soc. 2004 Jan 1; 1: 774-7.
AbstractAgitation-sedation cycling in critically ill patients, characterized by oscillations between states of agitation and over-sedation, damages patient health and increases length of stay and cost. The model presented captures the essential dynamics of the agitation-sedation system, is physiologically representative, and is validated by accurately simulating patient response for 37 critical care patients. The model provides a platform to develop and test controllers that offer the potential of improved agitation management.
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