• Crit Care Nurs Clin North Am · Sep 2014

    Review

    Microcirculatory oxygen transport and utilization.

    • Shannan K Hamlin, C Lee Parmley, and Sandra K Hanneman.
    • Nursing Research and Evidence-Based Practice, Houston Methodist Hospital, MGJ 11-017, Houston, TX 77030, USA. Electronic address: SHamlin@HoustonMethodist.org.
    • Crit Care Nurs Clin North Am. 2014 Sep 1; 26 (3): 311-24.

    AbstractThe cardiovascular system (macrocirculation) circulates blood throughout the body, but the microcirculation is responsible for modifying tissue perfusion and adapting it to metabolic demand. Hemodynamic assessment and monitoring of the critically ill patient is typically focused on global measures of oxygen transport and utilization, which do not evaluate the status of the microcirculation. Despite achievement and maintenance of global hemodynamic and oxygenation goals, patients may develop microcirculatory dysfunction with associated organ failure. A thorough understanding of the microcirculatory system under physiologic conditions will assist the clinician in early recognition of microcirculatory dysfunction in impending and actual disease states.Copyright © 2014 Elsevier Inc. All rights reserved.

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