• Anesthesia progress · Jan 1995

    Case Reports

    Type I second-degree AV block after neostigmine administration in a child with renal failure.

    • M D Webb.
    • Department of Pediatric Dentistry, Baylor College of Dentistry, Dallas, Texas 75246, USA.
    • Anesth Prog. 1995 Jan 1; 42 (1): 21-2.

    AbstractNeostigmine is commonly used to reverse neuromuscular blockade. A side effect can be parasympathetic stimulation, which may result in heart block. Renal failure can decrease the clearance and increase the half-life of the drug, thus increasing the likelihood of a vagomimetic response. A case is presented where a child with renal failure developed a type I second-degree heart block after neostigmine was given.

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