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Eur Heart J Acute Cardiovasc Care · Jun 2012
Lactate and lactate clearance in acute cardiac care patients.
- Paola Attanà, Chiara Lazzeri, Claudio Picariello, Carlotta Sorini Dini, Gian Franco Gensini, and Serafina Valente.
- Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
- Eur Heart J Acute Cardiovasc Care. 2012 Jun 1; 1 (2): 115-21.
AbstractHyperlactataemia is commonly used as a diagnostic and prognostic tool in intensive care settings. Recent studies documented that serial lactate measurements over time (or lactate clearance), may be clinically more reliable than lactate absolute value for risk stratification in different pathological conditions. While the negative prognostic role of hyperlactataemia in several critical ill diseases (such as sepsis and trauma) is well established, data in patients with acute cardiac conditions (i.e. acute coronary syndromes) are scarce and controversial. The present paper provides an overview of the current available evidence on the clinical role of lactic acid levels and lactate clearance in acute cardiac settings (acute coronary syndromes, cardiogenic shock, cardiac surgery), focusing on its prognostic role.
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