• Domenico A Restivo, Antonino Casabona, Diego Centonze, Rosario Marchese-Ragona, Davide Maimone, and Antonino Pavone.
• Department of Neurology, Nuovo Garibaldi Hospital, via Palermo, 95100 Catania, Italy. darestivo@libero.it
• Brain Stimul. 2013 May 1; 6 (3): 418-23.

ObjectiveTreatment options for dysphagia associated with multiple sclerosis (MS) are currently limited. In this study we investigated whether intraluminal electrical pharyngeal stimulation facilitates swallowing recovery in dysphagic MS patients.Patients And MethodsTwenty dysphagic MS patients were randomized to receive 5 Hz "real" pharyngeal stimulation (10 patients) for 10 min or "sham" pharyngeal stimulation for 10 min (10 patients). Patients were evaluated by videofluoroscopic, and electromyographic examinations, and by the Penetration/Aspiration Scale (PAS) performed before (T0) and immediately after the last session of 5 consecutive days of electrical pharyngeal stimulation (T1), and then after two (T2), and four (T3) weeks of 5 consecutive days of pharyngeal electrical stimulation.ResultsPatients who received "real" stimulation showed a significant improvement in all the swallowing outcome measures as compared with those receiving "sham" stimulation.ConclusionsNo specific treatment for oro-pharyngeal dysphagia related to MS has been described to date. Our preliminary findings suggest a potential benefit of intraluminal electrical pharyngeal stimulation for the treatment of dysphagia caused by MS.Copyright © 2013 Elsevier Inc. All rights reserved.

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