• Intensive care medicine · Mar 1996

    Case Reports

    Pain relief with low-dose intravenous clonidine in a child with severe burns.

    • B Lyons, W Casey, P Doherty, M McHugh, and K P Moore.
    • Dept. of Anaesthesia, Our Lady's Hospital for Sick Children, Dublin, Ireland.
    • Intensive Care Med. 1996 Mar 1; 22 (3): 249-51.

    AbstractThe case of an 11-year-old boy who suffered second and third degree burns to 78% of his body is reported. The large doses of morphine used as analgesia resulted in severe side effects: ventilatory dependence, impairment of gastrointestinal function and psychological disturbance. Intravenous lignocaine was added without benefit. The addition of low-dose intravenous clonidine, however, precipitated a dramatic reduction in morphine consumption with an attendant improvement in ventilatory, gastrointestinal and psychological functions.

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