• Ned Tijdschr Geneeskd · Dec 2006

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    [Limited possibilities for the evidence-based treatment and prevention of postherpetic neuralgia].

    • W W A Zuurmond and R S G M Perez.
    • VU Medisch Centrum, afd. Anesthesiologie, Postbus 7057, 1007 MB Amsterdam. wwa.zuurmond@vumc.nl
    • Ned Tijdschr Geneeskd. 2006 Dec 2; 150 (48): 2633-6.

    AbstractPostherpetic neuralgia is a disorder that occurs frequently in the elderly. As the effect of the treatment of postherpetic neuralgia is often disappointing, studies have focussed on the prevention of this complaint. A commonly used preventive intervention is the administration ofa single epidural injection of a local anaesthetic and a corticosteroid, combined with oral antiviral agents and analgesics. In a large, multicentre, randomised controlled trial, the investigators found that the single injection of a corticosteroid and a local anaesthetic had no added value in the prevention of long-term postherpetic neuralgia.

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