• Ugeskrift for laeger · Jan 2006

    Review

    [Levosimendan--an alternative to conventional inotropic treatment of patients with acute heart failure?].

    • Thomas Rasmussen and Henrik Schmidt.
    • Holbaek Sygehus, Anaestesiologisk Afdeling, og Odense Universitetshospital. drrasmussen@hotmail.com
    • Ugeskr. Laeg. 2006 Jan 16; 168 (3): 261-5.

    AbstractIn acute heart failure the myocardial function is acutely reduced and the oxygenation of the tissues becomes inadequate. Traditional inotropic drugs improve the haemodynamics and give symptomatic relief, but the evidence of injurious effects on morbidity and mortality restricts their use. The need for new inotropic drugs which can also reduce morbidity and mortality is for that reason obvious. Levosimendan is such a new drug in a new class (Ca2+ sensitizers) of positive inotropic drugs with favourable effects compared to existing treatment possibilities.

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