• Cns Spectrums · Dec 2014

    Review

    Mechanism of action of tasimelteon in non-24 sleep-wake syndrome: treatment for a circadian rhythm disorder in blind patients.

    • Stephen M Stahl.
    • Cns Spectrums. 2014 Dec 1; 19 (6): 475-8.

    IssueMany individuals with total blindness can develop a circadian rhythm disorder-called non-24 sleep wake syndrome-because they cannot detect light to resynchronize their sleep-wake cycles. A new melatonin 1 and melatonin 2 agonist tasimelteon improves sleep in these patients, resetting their circadian sleep-wake clocks.

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