• Hatice Ayhan, Sevinc Tastan, Emine Iyigun, Yagmur Akamca, Elif Arikan, and Zubeyde Sevim.
• School of Nursing, Gulhane Military Medical Academy, Ankara, Turkey. Electronic address: hayhan@gata.edu.tr.
• J Crit Care. 2015 Aug 1;30(4):762-7.

PurposeThis study aimed to systematically review studies that investigated the effects of normal saline instillation before endotracheal suctioning and to determine the views of nurses concerning this procedure.MethodsThis study was carried out in 2 stages as a systematic review and a descriptive study. In the first stage, the Medline and CINAHL databases were searched. The second stage of the study consisted of a survey of 65 intensive care nurses.ResultsThe systematic review identified 7 studies. Nearly all of the studies had a self-controlled clinical trial design. Normal saline instillation before endotracheal suctioning was demonstrated to decrease patient oxygenation in most studies (P < .05). However, the impact of normal saline on hemodynamics and the incidence of ventilator-associated pneumonia remain unclear. Most nurses (87.7%) apply normal saline instillation.ConclusionAlthough the effects of normal saline instillation on hemodynamics and pneumonia incidence remain controversial, this procedure significantly decreases the oxygenation. Therefore, the use of this procedure is not recommended. However, normal saline instillation is used frequently by nurses to manage thick and tenacious secretions in clinical practice. Additional studies are needed to determine the effectiveness of applications that may be alternatives to normal saline instillation in the management of these secretions.Copyright © 2015. Published by Elsevier Inc.

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