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La Tunisie médicale · Apr 2012
Review[Pathophysiology of complex regional pain syndrome (CRPS) type 1].
- Dalila Mrabet, Chekib Khemiri, Ines Ben Mrad, Hela Mrabet, Hamza Essaddem, Mrabet Amel, Hela Sahli, and Slaheddine Sellami.
- Service de Rhumatologie, EPS La Rabta, Tunis.
- Tunis Med. 2012 Apr 1; 90 (4): 278-81.
BackgroundIf the pathophysiology of complex regional pain syndrome (CRPS) type 1 remains controversial, most authors agree on a combination in varying proportions, a sensitization of peripheral nerves.AimTo describe the state of advances in the physiopathology of complex regional pain syndrome type 1.MethodsBibliographic research and literature review performed by referring to databases (Medline, Science Direct)ResultsThe physiopathology of complex regional pain syndrome type 1 remains still poorly understood and controversial. Several arguments demonstrated both peripheral (inflammation, abnormal sympathetic ...) and central (neurological and cognitive) mechanisms.ConclusionA better knowledge of the physiopathology of complex pain syndrome type 1 is necessary in order to adapt efficient curative therapy or to a better prevention of this syndrome.
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