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Randomized Controlled Trial Clinical Trial
Transcutaneous electrical nerve stimulation treatment of sickle cell pain crises.
- W C Wang, S L George, and J A Wilimas.
- Department of Hematology-Oncology, St. Jude Children's Research Hospital, Memphis, Tenn.
- Acta Haematol. 1988 Jan 1; 80 (2): 99-102.
AbstractTranscutaneous electrical nerve stimulation (TENS) has been used in a variety of acute and chronic painful conditions, but has not been studied in sickle cell pain crises. We compared TENS versus placebo in a randomized, double-blind, cross-over study involving 60 trials in 4 crisis severity categories. TENS electrodes were applied to the area of severest pain and patients' pain ratings and medication usage were evaluated over a 4-hour period. Pain ratings and analgesic requirements at 1 and 4 h from onset of study were similar in the TENS and placebo groups. Patients assessments of overall treatment efficacy indicated that TENS was more frequently helpful, but there was a substantial placebo effect. Although the value of TENS in this condition was not established in this study, further trials, using varied stimulation parameters, are warranted.
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