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Zhonghua yi xue za zhi · Oct 2010
Randomized Controlled Trial[Premedication with oral midazolam in children receive sevoflurane general anesthesia].
- Xue-ying Jiang, Tian-zuo Li, and Li Li.
- Department of Anesthesiology, Capital Medical University, Beijing 100730, China.
- Zhonghua Yi Xue Za Zhi. 2010 Oct 12; 90 (37): 2633-5.
ObjectiveTo investigate the effect of oral midazolam on sedation, on perioperative emotion and on behavior in children with sevoflurane general anesthesia.Methods48 children undergoing cataract surgeries were randomly divided into two groups and respectively received 0.5 mg/kg oral midazolam (Group I)and placebo (Group II) 30 minutes before the operation. Perioperative behavior and emotion status were assessed.ResultsSatisfactory sedation ratio in group I was better than that in group II (58.3% vs 12.5%, P < 0.05). There were no differences in emergence time, PACU stay and incidence of emergence agitation between two groups (P > 0.05).Conclusion0.5 mg/kg oral midazolam before sevoflurane general anesthesia in children is safe. It is effective on anxious relief, however it does not decrease the incidence of emergence agitation.
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