• Aging Clin Exp Res · Dec 2008

    Case Reports

    Hepatotoxicity after intravenous amiodarone.

    • Angelo Cataldi, Davide Gonella, Nadia Robutti, Mario Siri, Serena Buonocore, and Patrizio Odetti.
    • Department of Internal Medicine and Medical Specialties, University of Genova, 16132 Genova, Italy. angicat@libero.it
    • Aging Clin Exp Res. 2008 Dec 1; 20 (6): 593-6.

    AbstractAmiodarone is a class III antiarrhythmic agent with a long half-life which is used to control atrial and ventricular arrhythmias, including atrial flutter and fibrillation. We describe here the case of an elderly woman (77 years of age) who was hospitalized for acute atrial fibrillation, abdominal pain, and dyspnea. In the Emergency Department, treatment with intravenous amiodarone was begun. The following day, the patient developed acute liver damage; improved liver function occurred following the withdrawal of amiodarone. Complete recovery of liver function was documented after three weeks. Unfortunately, the patient died from a severe infectious disease, with multiple organ failure.

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