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Case Reports
Severe lactic acidosis and multiorgan failure due to thiamine deficiency during total parenteral nutrition.
- Musaab Ramsi, Claire Mowbray, Gary Hartman, and Natalie Pageler.
- Department of Pediatric Critical Care, Stanford University, Palo Alto, California, USA.
- BMJ Case Rep. 2014 Jan 1; 2014.
AbstractA 16-year-old perioperative paediatric patient presented with refractory lactic acidosis and multiorgan failure due to thiamine-deficient total parenteral nutrition during a recent national multivitamin shortage. Urgent empiric administration of intravenous thiamine resulted in prompt recovery from this life-threatening condition. Despite readily available treatment, a high index of suspicion is required to prevent cardiovascular collapse and mortality.2014 BMJ Publishing Group Ltd.
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