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Controlled Clinical Trial
Prospective study of early detection of pharyngeal superficial carcinoma with the narrowband imaging laryngoscope.
- Toru Ugumori, Manabu Muto, Ryuichi Hayashi, Tomomasa Hayashi, and Seiji Kishimoto.
- Division of Head and Neck Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha Kashiwa-city, Chiba 277-8577, Japan. ugumorit@m.ehime-u.ac.jp
- Head Neck. 2009 Feb 1; 31 (2): 189-94.
BackgroundThe newly developed narrowband imaging (NBI) gastrointestinal endoscope makes possible the detection of superficial carcinoma in the oropharynx and hypopharynx, which is difficult with the conventional laryngoscope. Here, we investigated whether the combined use of laryngoscope with NBI allows the detection of superficial carcinoma in this region.MethodsA total of 51 superficial, histologically confirmed lesions in 29 patients were studied. The quality of visualization of superficial carcinoma in the oropharynx and hypopharynx using the NBI-equipped laryngoscope was evaluated in comparison with the results by conventional laryngoscopy.ResultsThe NBI laryngoscope provided better detection of the irregular microvascular pattern of carcinoma than the conventional laryngoscope (p <.05) and better visualization of the demarcation line (p <.05), and thus significantly better visualization of the lesions.ConclusionThe NBI laryngoscope may play an important role in the diagnosis and treatment of superficial carcinoma in the oropharynx and hypopharynx.
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