• Wien. Klin. Wochenschr. · Aug 2010

    Review

    [Sedation and analgesia in intensive care: physiology and application].

    • David M Baron, Philipp G H Metnitz, and Burkhard Gustorff.
    • Univ.Klinik für Anästhesie, Allgemeine Intensivmedizin und Schmerztherapie, Medizinische Universität Wien, Wien, Austria.
    • Wien. Klin. Wochenschr. 2010 Aug 1; 122 (15-16): 455-64.

    AbstractMany therapeutic and diagnostic procedures in intensive care medicine are perceived as painful by most patients. As a consequence analgesia and sedation represent two of the main pillars in the treatment of the critically ill. Adaptation to the individual needs of the patients poses one of the biggest challenges that we are confronted with. Both morbidity and mortality can be positively influenced by adequate treatment. In the first part of this review we will discuss the physiology of sleep patterns and pain. Furthermore modes of action and side effects of the most common anesthetics and analgetics will be presented. Finally, the last part of the manuscript deals with the practical application of these therapeutics and their monitoring in intensive care medicine.

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