• Ann Card Anaesth · Jan 2009

    Case Reports

    Induced mild hypothermia in post-cardiopulmonary bypass vasoplegia syndrome.

    • Mukesh Tripathi, Prabhat Kumar Singh, Naresh Kumar, and Kailash Chandra Pant.
    • Department of Anaesthesiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India. mukesh_tripathi@yahoo.com
    • Ann Card Anaesth. 2009 Jan 1; 12 (1): 49-52.

    AbstractThe state of vasoplegia in immediate post-cardiopulmonary bypass period is characterized by severe hypotension, supranormal cardiac output, low systemic vascular resistance (SVR), and resistance to vasoconstrictors. We could successfully use induced mild hypothermia to increase SVR, and could avoid very high doses of nor-epinephrine (>0.3 mcg/kg/min) in the background of severe pulmonary hypertension (systolic pulmonary pressure> 90 mmHg). Its effects such as decreased oxygen demand, positive inotropy and better right ventricle performance probably helped to improve oxygenation in presence of pulmonary oedema.

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