• Psychogeriatrics · Dec 2012

    Case Reports

    Marked improvement in delirium with ramelteon: five case reports.

    • Motohide Furuya, Tsuyoshi Miyaoka, Hideaki Yasuda, Satoko Yamashita, Ippei Tanaka, Shoko Otsuka, Rei Wake, and Jun Horiguchi.
    • Department of Psychiatry, Faculty of Medicine, Shimane University School, Izumo, Japan. pancho@med.shimane-u.ac.jp
    • Psychogeriatrics. 2012 Dec 1; 12 (4): 259-62.

    AbstractDelirium is a common and serious acute neuropsychiatric syndrome characterized by inattention and global cognitive dysfunction. Delirium is associated with higher morbidity, higher mortality and longer hospitalization, but its aetiology remains unclear. We successfully treated five cases of delirium within 1 day with ramelteon, a novel selective melatonin receptor agonist. This suggests that correction of the circadian rhythm disturbance, one of the main symptoms of delirium, plays a crucial role in its treatment and sheds new light on a therapeutic strategy for treatment of delirium.© 2012 The Authors. Psychogeriatrics © 2012 Japanese Psychogeriatric Society.

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