• J. Neurol. Neurosurg. Psychiatr. · May 1991

    Case Reports

    A case of progressive encephalomyelitis with rigidity and positive antiglutamic acid decarboxylase antibodies [corrected].

    • D J Burn, J Ball, A J Lees, P O Behan, and J A Morgan-Hughes.
    • Hammersmith Hospital, London, UK.
    • J. Neurol. Neurosurg. Psychiatr. 1991 May 1; 54 (5): 449-51.

    AbstractA 50 year old woman developed progressive encephalomyelitis with rigidity over a three year period. Her CSF contained oligoclonal bands and both her serum and CSF contained antibodies directed against GABA-ergic synapses (antiglutamic acid decarboxylase [corrected] antibodies). These antibodies have recently been described in cases of stiff man syndrome. Both disorders may be part of a clinical spectrum that has an underlying autoimmune basis.

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