• Med Klin · Apr 2005

    Comparative Study

    [Long-term outcome of intrapleural fibrinolytic therapy via small-bore catheter drainage in the management of complicated parapneumonic effusion and empyema-a case series].

    • Selçuk Tasci, Alexandra Burghard, Harald Schäfer, Christian Rabe, Santiago Ewig, and Berndt Lüderitz.
    • Medizinische Klinik und Poliklinik II, Universitätsklinikum, Bonn. Selcuk.Tasci@ukb.uni-bonn.de
    • Med Klin. 2005 Apr 15; 100 (4): 181-5.

    Background And PurposeComplicated parapneumonic effusions (PPE) and pleural empyemas (PE) are associated with increased morbidity and mortality. Intrapleural fibrinolytic therapy (IFT) has been established, besides video-assisted thoracoscopy (VATS), in the management of PPE and PE. Combination of IFT and small-bore catheter drainage has previously not been investigated.Patients And Methods15 patients consecutively referred for PPE and PE were managed with simultaneous IFT via small-bore catheter drainage (9, 12, 14 F). In addition to evaluation of primary outcome, lung function testing and radiologic studies were obtained after 3 months to predict potential pulmonary restrictive impairment and residual pleural thickening.ResultsPrimary outcome of all 15 patients was positive. Only one patient showed a significant residual pleural thickening. None of the patients showed a restrictive lung function pattern.ConclusionProven applicability of IFT via small-bore catheter drainage seems to be effective in the face of long-term outcome. Further prospective and multicentric studies should be initiated to investigate the practicability of IFT via small-bore catheter drainage.

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