• Seiichiro Yoshioka, Tomoyuki Takano, Fukiko Ryujin, and Yoshihiro Takeuchi.
• Department of Pediatrics, Shiga University of Medical Science, Shiga, Japan. yoshioka1974830@yahoo.co.jp
• Brain Dev. 2012 Oct 1; 34 (9): 796-8.

AbstractReversible cerebral vasoconstriction syndrome (RCVS) is a rare disorder characterized by acute onset, severe headache, with reversible vasoconstriction of cerebral arteries often accompanied by additional neurological symptoms. This syndrome is seen mainly in middle-aged adults, predominantly women. Herein, we report on a pediatric case of RCVS with cortical subarachnoid hemorrhage (SAH). A 12-year-old boy developed acute, severe headache with paralysis of lower extremities causing gait disturbance after administration of eletriptan. Brain magnetic resonance angiography (MRA) revealed multifocal narrowing of the cerebral arteries, whereas magnetic resonance imaging (MRI) demonstrated sulcal hyperintensity on fluid-attenuated inversion recovery, consistent with cortical SAH. The patient's clinical symptoms resolved spontaneously after a few days and the MRI and MRA findings disappeared 3 months later, suggesting a diagnosis of RCVS. Eletriptan might cause vasoconstriction of cerebral arteries. Although most patients with RCVS are adults and pediatric cases are rare, RCVS should be considered in a child complaining of severe headache.Copyright © 2012 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

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