• Biomarkers · Mar 2012

    Assessment of risk factors for in-hospital mortality after intensive care unit discharge.

    • Inês Araújo, João Gonçalves-Pereira, Sofia Teixeira, Raquel Nazareth, Joana Silvestre, Vítor Mendes, Camila Tapadinhas, and Pedro Póvoa.
    • Polyvalent Intensive Care Unit, São Francisco Xavier Hospital, CHLO, Lisboa, Portugal. inesarauj@gmail.com
    • Biomarkers. 2012 Mar 1; 17 (2): 180-5.

    ContextPost-intensive care unit (ICU) mortality predictors are unknown.ObjectiveTo assess post-ICU in-hospital mortality predictors.Materials And MethodsAnalysis of 296 patients discharged alive from a medical-surgical ICU during an 18-month period.ResultsPost-ICU in-hospital mortality was 22.6%. Nonsurvivors had significantly higher Charlson comorbidity score and more often had a tracheostomy. C-reactive protein (CRP) "alert measurement", ≥ 6 mg/dL, independently discriminated survivors from nonsurvivors.DiscussionA CRP "alert measurement" or the need for tracheostomy may be used to identify patients with high risk of dying after ICU discharge.ConclusionsCharlson comorbidity score, CRP and tracheostomy predicted post-ICU in-hospital mortality.

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