-
Review Case Reports
[Pediatric acute lymphoblastic leukemia initially presenting with bone marrow necrosis].
- Motohiro Kato, Akira Kikuchi, Koichi Oshima, Syohei Yamamoto, Shinji Mochizuki, Kokoro Arai, and Ryoji Hanada.
- Saitama Children's Medical Center, The Department of Hematology/Oncology.
- Rinsho Ketsueki. 2007 Feb 1; 48 (2): 140-3.
AbstractWe report on a case of pediatric acute lymphoblastic leukemia presenting with massive bone marrow necrosis. A 4-year-old boy complained of fever and leg pain. Laboratory data revealed pancytopenia, but bone marrow examination showed only necrotic materials. About one month later, repeated bone marrow examination showed leukemic cells and the necrotic marrow had disappeared. The patient was treated with standard chemotherapy and was successfully induced to complete remission. Patients with massive bone marrow necrosis should undergo bone marrow examination repeatedly to make the correct diagnosis.
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