• Neurosurg Focus · Sep 2015

    Ultrasound-guided percutaneous injection of methylene blue to identify nerve pathology and guide surgery.

    • Joseph A Osorio, Jonathan D Breshears, Omar Arnaout, Neil G Simon, Ashley M Hastings-Robinson, Pedram Aleshi, and Michel Kliot.
    • Department of Neurological Surgery, University of California, San Francisco, California;
    • Neurosurg Focus. 2015 Sep 1; 39 (3): E2.

    AbstractOBJECT The objective of this study was to provide a technique that could be used in the preoperative period to facilitate the surgical exploration of peripheral nerve pathology. METHODS The authors describe a technique in which 1) ultrasonography is used in the immediate preoperative period to identify target peripheral nerves, 2) an ultrasound-guided needle electrode is used to stimulate peripheral nerves to confirm their position, and then 3) a methylene blue (MB) injection is performed to mark the peripheral nerve pathology to facilitate surgical exploration. RESULTS A cohort of 13 patients with varying indications for peripheral nerve surgery is presented in which ultrasound guidance, stimulation, and MB were used to localize and create a road map for surgeries. CONCLUSIONS Preoperative ultrasound-guided MB administration is a promising technique that peripheral nerve surgeons could use to plan and execute surgery.

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