• Int Heart J · Sep 2005

    Case Reports

    Cough reflex by ventricular premature contractions.

    • Akio Niimi, Yasuki Kihara, Yoshiyuki Sumita, Yoshiaki Okano, Keiichi Tambara, and Masatoshi Fujita.
    • Division of Respiratory Medicine, Kyoto University Hospital, Japan.
    • Int Heart J. 2005 Sep 1; 46 (5): 923-6.

    AbstractA 72-year-old man was referred for further assessment of a chronic cough. He noticed an association between the episodes of coughing and palpitations. Electrocardiography (ECG) revealed normal sinus rhythm and sporadic unifocal ventricular premature contractions (VPCs). Each cough was preceded by a premature beat. Continuous wave Doppler echocardiography revealed a VPC-induced transient increase in the pulmonary artery blood flow. He was successfully treated for VPCs with oral disopyramide, resulting in subsidence of both the coughing and palpitations. We suspect that the VPC-induced hemodynamic changes in the pulmonary circulation might be responsible for coughing in our patient. Premature contractions should be considered as a possible cause of chronic dry cough in the clinical setting.

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