• Gynecologic oncology · Mar 2009

    Role of endocervical curettage in the preoperative staging of endometrial carcinoma.

    • Claudia B M Bijen, Geertruida H de Bock, Klaske A ten Hoor, Hans W Nijman, Harry Hollema, and Marian J E Mourits.
    • Department of Gynecologic Oncology, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.
    • Gynecol. Oncol. 2009 Mar 1; 112 (3): 521-5.

    ObjectiveThe presence of cervical involvement is important to establish a rational treatment for endometrial cancer patients. We investigated the value of preoperative endocervical curettage (ECC) in predicting cervical involvement.MethodsPreoperative ECC of 290 patients with clinical stage I epithelial endometrial cancer was compared with histopathology of the uterus.ResultsAmongst all ECCs, 245 (84.5%) were negative and 45 (15.5%) were positive for endometrial cancer. In the uterine specimen, cervical involvement was found in 20% (58/290). PPV and NPV of ECC were 86.7% and 92.2%. False negative and false positive ECC occurred in 6.6% and 2.1%. Of all patients with positive ECC, 46.7% had FIGO stage II disease and 46.7% had extra uterine tumor spread (FIGO III, IV).ConclusionECC is an acceptable diagnostic tool to predict the presence or absence of cervical involvement in early stage endometrial cancer patients.

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