(1)H MR spectroscopy in pediatrics.

Eur J Radiol · Aug 2008

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(1)H MR spectroscopy in pediatrics.

Spectral appearance and concentrations of the most prominent metabolites are affected by brain development. This knowledge is essential for the detection of pathological changes in pediatric patients. ⋯ Clinical examples show several diseases that are reflected in changes in (1)H MR spectra due to pathological alterations in the biochemical pathways of the observed metabolites. Attention is given to the main metabolites such as N-acetylaspartate, creatine/phosphocreatine, cholines, lactate, inositol, etc.

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- Monika Dezortova and Milan Hajek.
- MR Unit, Department of Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic. mode@medicon.cz <mode@medicon.cz>
- Eur J Radiol. 2008 Aug 1; 67 (2): 240-9.
AbstractSpectral appearance and concentrations of the most prominent metabolites are affected by brain development. This knowledge is essential for the detection of pathological changes in pediatric patients. This paper discusses specific conditions of MR spectroscopic examination of children and the effects of age on MR spectra quality and quantitation of the studied metabolites. Clinical examples show several diseases that are reflected in changes in (1)H MR spectra due to pathological alterations in the biochemical pathways of the observed metabolites. Attention is given to the main metabolites such as N-acetylaspartate, creatine/phosphocreatine, cholines, lactate, inositol, etc.

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(1)H MR spectroscopy in pediatrics.

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