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- S Gan, L Song, W Chen, Z Feng, Y Li, J Zhang, and S Zhu.
- Department of Anaesthesiology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
- Anaesthesia. 2015 Sep 1;70(9):1060-5.
AbstractWe injected 15 ml epidural ropivacaine in 30 men and 30 women to determine the median dose required to impair a straight-leg raise. We started at a concentration of 0.425%, increasing the concentration by 0.025% after an ineffective injection and decreasing the concentration by 0.025% after an effective injection. The median (95% CI) concentration of ropivacaine that prevented straight-leg raise within 30 min of injection was 0.43% (0.41-0.45%) in men and 0.40% (0.39-0.41%) in women, p = 0.001. There were no differences in dermatome levels for loss of pinprick and cold sensation between men and women.© 2015 The Association of Anaesthetists of Great Britain and Ireland.
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