• Anesthesia and analgesia · Nov 2004

    Case Reports

    Suspected central anticholinergic syndrome in a 6-week-old infant.

    • Peter J Kulka, Hakki Toker, Jörg Heim, Alexander Joist, and Jens Jakschik.
    • Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Prosper-Hospital, Mühlenstrasse 27, D-45659 Recklinghausen, Germany. peter.kulka@prosper-hospital.de
    • Anesth. Analg. 2004 Nov 1; 99 (5): 1376-8; table of contents.

    AbstractA 6-wk-old male infant became unresponsive after an uneventful general anesthetic for hernia repair. His symptoms were consistent with central anticholinergic syndrome. He appeared to awaken after treatment with IV physostigmine in a dose of 0.04 mg/kg. Because of the recurrence of sedation, a second physostigmine infusion was administered, which again led to transient arousal. Finally, the patient awoke spontaneously after 24 h and recovered uneventfully.

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