• Do Young Kim, Sang-Wook Kang, Dae Suk Kim, Jung U Shin, Woong Youn Chung, Cheong Soo Park, Ju Hee Lee, and Kee-Hyun Nam.
• *Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea; †Department of Surgery, Institute of Endocrine Research, Yonsei University College of Medicine, Seoul, Korea.
• Dermatol Surg. 2015 Jul 1; 41 (7): 812-20.

BackgroundAcellular dermal matrix (ADM) has been used for antiadhesion formation along with wound healing in various surgical fields.ObjectiveThe aim is to assess the efficacy of ADM implantation in the prevention of postoperative scars and adhesions after conventional, open, total thyroidectomy.Materials And MethodsForty-four patients with papillary thyroid carcinoma undergoing thyroidectomy were randomly assigned to the study (ADM implantation) or control group (without ADM). Global photographic assessment, Vancouver scar scale (VSS), objective scar assessment, and swallowing impairment index were assessed at baseline, immediately after surgery, and at 1 and 2 months after surgery.ResultsNineteen control and 20 study group participants completed the study. The mean VSS score of the study group was significantly lower than the controls at both 1 month (3.06 ± 1.25 vs 4.41 ± 1.54, respectively) and 2 months (2.76 ± 1.56 vs 4.35 ± 1.58, respectively) after surgery. Scar quality measures (mean melanin and erythema indexes) were significantly lower in the study group compared with controls. Study group participants had significantly lower swallowing impairment scores than controls. The mean postoperative hospitalization of both groups was not significantly different.ConclusionAcellular dermal matrix-assisted implants appear to improve post-thyroidectomy scar and swallowing impairments without delays in operation time.

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