• TheScientificWorldJournal · Jan 2012

    Randomized Controlled Trial

    Correlation of surgical pleth index with stress hormones during propofol-remifentanil anaesthesia.

    • Xinzhong Chen, Carsten Thee, Matthias Gruenewald, Christoph Ilies, Jan Höcker, Robert Hanss, Markus Steinfath, and Berthold Bein.
    • Department of Anaesthesia, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310058, China. chenxinz@zju.edu.cn
    • ScientificWorldJournal. 2012 Jan 1; 2012: 879158.

    AbstractEighty patients undergoing elective ear-nose-throat surgery were enrolled in the present study to investigate the relationship between surgical pleth index (SPI) and stress hormones (ACTH, cortisol, epinephrine, norepinephrine) during general anaesthesia which was induced and maintained with propofol and remifentanil using a target-controlled infusion. The study concluded that the SPI had moderate correlation to the stress hormones during general anaesthesia, but no correlation during consciousness. Furthermore, SPI values were able to predict ACTH values with high sensitivity and specificity.

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