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Anesthesia and analgesia · Jan 2003
Oral tramadol for the treatment of pain of 7-30 days' duration in children.
- John B Rose, Julia C Finkel, Adriano Arquedas-Mohs, Bruce P Himelstein, Mark Schreiner, and Robert A Medve.
- Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Pennsylvania 19104, USA. rose@email.chop.edu
- Anesth. Analg. 2003 Jan 1; 96 (1): 78-81, table of contents.
ImplicationsThis open-label, multicenter trial was designed to determine the safety profile and analgesic efficacy of tramadol for the treatment of painful conditions lasting 7-30 days in 7-16-yr-old children. We found that tramadol 1-2 mg/kg per os every 4-6 h (maximal dose = 8 mg x kg(-1). d(-1), not to exceed 400 mg/d) is a safe and effective analgesic in this patient population.
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