• Fernanda Machado Kutchak, Andressa Maciel Debesaitys, Marcelo de Mello Rieder, Carla Meneguzzi, Amanda Soares Skueresky, Luiz Alberto Forgiarini Junior, and Marino Muxfeldt Bianchin.
• Universidade do Vale do Rio dos Sinos, São Leopoldo, RS, BR.
• J Bras Pneumol. 2015 Jul 1; 41 (4): 358-64.

ObjectiveTo evaluate the use of reflex cough PEF as a predictor of successful extubation in neurological patients who were candidates for weaning from mechanical ventilation.MethodsThis was a cross-sectional study of 135 patients receiving mechanical ventilation for more than 24 h in the ICU of Cristo Redentor Hospital, in the city of Porto Alegre, Brazil. Reflex cough PEF, the rapid shallow breathing index, MIP, and MEP were measured, as were ventilatory, hemodynamic, and clinical parameters.ResultsThe mean age of the patients was 47.8 ± 17 years. The extubation failure rate was 33.3%. A reflex cough PEF of < 80 L/min showed a relative risk of 3.6 (95% CI: 2.0-6.7), and the final Glasgow Coma Scale score showed a relative risk of 0.64 (95% CI: 0.51-0.83). For every 1-point increase in a Glasgow Coma Scale score of 8, there was a 36% reduction in the risk of extubation failure.ConclusionsReflex cough PEF and the Glasgow Coma Scale score are independent predictors of extubation failure in neurological patients admitted to the ICU.

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