• Am. J. Crit. Care · May 2015

    Case Reports

    A case of thyrotoxic periodic paralysis with respiratory failure in an african american woman.

    • Denise L Shields.
    • Denise L. Shields is an acute care nurse practitioner at Robert Wood Johnson University Hospital, Hamilton Township, New Jersey. DeniseShields@verizon.net.
    • Am. J. Crit. Care. 2015 May 1;24(3):264-7.

    AbstractThyrotoxic periodic paralysis is an acute endocrine emergency characterized by hyperthyroidism, profound muscle weakness and/or paralysis, and hypokalemia that is not due to potassium deficiency. Typically described in young males of Asian descent, it is becoming increasingly recognized outside of this demographic group and is believed to be an underrecognized cause of symptomatic hypokalemia. Thyrotoxic periodic paralysis usually manifests as acute onset of symmetrical distal extremity weakness and is treated with careful potassium replacement and nonselective β-blockers. In this case, a 43-year-old African American woman with thyrotoxic periodic paralysis had recurrent lower extremity myopathy and acute respiratory failure precipitated by noncompliance with treatment for Graves disease.©2015 American Association of Critical-Care Nurses.

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