• J Oral Surg · Jul 1978

    Comparative Study

    Microscarring in skeletal muscle after repeated exposures to lidocaine with epinephrine.

    • P W Benoit.
    • J Oral Surg. 1978 Jul 1; 36 (7): 530-3.

    AbstractTo assess the effect of repeated exposures to clinically used local anesthetic, rat thighs were given up to five supramuscular injections of 2% lidocaine with epinephrine, 1:50,000. Substantial damage to muscles followed by rapid regeneration occurred; however, in some areas evidence of retarded regeneration of muscles and microscarring was observed.

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