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Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi · May 2013
Review[Research progress of mesenchymal stem cells in burn wound repair].
- Yusen Huo, Hongjie Duan, Lingying Liu, Quan Hu, and Jiake Chai.
- Department of Burn & Plastic Surgery, the First Affiliated Hospital of Chinese PLA General Hospital, Beijing, 100037, PR China.
- Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2013 May 1; 27 (5): 571-4.
ObjectiveTo review the research progress of mesenchymal stem cells (MSCs) in burn wound repair.MethodsThe recent literature about MSCs involved in burn wound repair and mechanism was extensively reviewed and analyzed.ResultsMSCs have the capacity of self-renew, rapid proliferation, differentiation and paracrine, and promote burn wound repair through differentiating into a series of skin wound cells and regulating wound microenvironment.ConclusionMSCs have great potentials in the burn field. However, the cell survival and outcome are also facing challenges from poor microenvironment of the burn wound.
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