• Epilepsy research · Mar 2014

    Comorbidity between headache and epilepsy in a Chinese epileptic center.

    • Xiang-Qing Wang, Sen-Yang Lang, Xu Zhang, Fei Zhu, Min Wan, Xiao-Bing Shi, Yun-Feng Ma, Mian-Wang He, and Sheng-Yuan Yu.
    • Department of Neurology, Chinese PLA General Hospital, No. 28, Fuxing Road, Beijing 100853, China. Electronic address: bjxqwang@yahoo.com.cn.
    • Epilepsy Res. 2014 Mar 1; 108 (3): 535-41.

    AbstractHere we investigated the characteristics and prevalence of headaches in patients with epilepsy in a Chinese epileptic center based on the International Classification of Headache Disorders, 2nd edition. We found that 60.14% (667/1109) of patients reported headaches. Headache was less prevalent in males (57.17%) than in females (63.75%). Interictal headaches were present in 34.62% of patients, and 139/1109 (12.53%) patients had interictal migraine, which was a higher percentage than reported in a large population-based study from the same area (9.3%) using the same screening question. In addition, 469 (70.31%) patients had postictal headache, migraine characteristics were present in 73.35% of these patients, and 15.35% also suffered from interictal migraine. Lastly, 8.85% patients had preictal headache. These results confirm that headache is very common in patients with epilepsy. Seizures often trigger postictal headaches with migraine features. The comorbidity of migraines and epilepsy should receive clinical attention, as it may influence antiepileptic drug choice, and the headache may require specific treatment.Copyright © 2013 Elsevier B.V. All rights reserved.

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