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Am J Alzheimers Dis Other Demen · Aug 2015
ApoE type 4 allele affects cognitive function of aged population in Tianjin City, China.
- Shoudan Sun, Jingming Fu, Jun Chen, Wei Pang, Ruomei Hu, Haiqiang Li, Long Tan, and Yugang Jiang.
- Department of Nutrition, Tianjin Institute of Health & Environmental Medicine, Tianjin, China Department of Nutrition, Tianjin Hospital, Tianjin, China.
- Am J Alzheimers Dis Other Demen. 2015 Aug 1; 30 (5): 503-7.
AbstractApolipoprotein E type 4 allele (ApoE∊4) is known as a risk gene for the late-onset Alzheimer's disease, and the relationship between ApoE∊4 and cognitive function of the elderly people has drawn the attention of the scientists. In this study, we investigated the relationship between ApoE∊4 and the cognitive function of the old people. A total of 156 old people were investigated, of whom 31 were ApoE∊4 carriers. The ApoE∊4 primarily influenced the global cognitive function, perceptual speed, and work memory. The results indicate that ApoE∊4 has significant negative effect on the cognitive function of the elderly people who are 60 years and older.© The Author(s) 2015.
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