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Ugeskrift for laeger · Oct 2011
Case Reports[Fatal succinylcholine-induced hyperkalemia in an intensive care unit].
- Benedikte Frederiksen, Morten Steensen, and Peder Carl.
- Intensiv Afdeling 542, Hvidovre Hospital, 2650 Hvidovre, Denmark. benediktesf@yahoo.com
- Ugeskr. Laeg. 2011 Oct 24; 173 (43): 2704-5.
AbstractSuccinylcholine-induced hyperkalemia is reported, but is still used in rapid sequence induction. In our case a 44 year-old man with septic shock was mechanically ventilated for 13 days, extubated but because of respiratory insufficiency reintubated. During induction an increase in p-potassium (4.2-11.7 mmol/l) caused ventricular fibrillation. Immobilization/infection cause an up-regulation and change in acetylcholine receptors is probably the reason for the extensive hyperkalemia and death. Caution in using succinylcholine is recommended and using rocuronium as an alternative is discussed.
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