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G Ital Cardiol (Rome) · Jul 2015
[An increase of infective endocarditis cases in England seen with concomitant reduction in antibiotic prophylaxis since the implementation of NICE guidelines in 2008: possible explanations].
- Simon Tiberi, Frederick Pink, Angelina Jayakumar, and Francesco Arioli.
- Department of Infection, Royal London Hospital, Barts Healthcare NHS Trust, London, UK.
- G Ital Cardiol (Rome). 2015 Jul 1; 16 (7-8): 405-8.
AbstractDayer and colleagues recently reported in The Lancet an increased incidence of infective endocarditis in England since 2008, year of NICE guideline on the restriction of antibiotic prophylaxis. They observed a concomitant decrease in the use of antibiotic prophylaxis. The temporal link between reduction of prophylaxis prescribing and increase of infective endocarditis raises the question of whether there is a causal association. In view of this observation, should we rethink antibiotic prophylaxis to prevent infective endocarditis?
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