• Paediatric anaesthesia · Aug 2005

    Case Reports

    Noninvasive ventilation options in pediatric myasthenia gravis.

    • Marco Piastra, Giorgio Conti, Elena Caresta, Alessia Tempera, Antonio Chiaretti, Giancarlo Polidori, and Massimo Antonelli.
    • Pediatric Intensive Care Unit, Catholic University School of Medicine, Rome, Italy. marco.piastra@fastwebnet.it
    • Paediatr Anaesth. 2005 Aug 1; 15 (8): 699-702.

    AbstractA 10-month-old female infant with congenital myasthenic syndrome suffering from acute respiratory failure was supported using face mask positive pressure ventilation until definitive diagnosis and specific treatment was achieved. A 12-year-old girl suffering from seronegative myasthenia gravis was treated by helmet-delivered noninvasive ventilation during recurrent myasthenic episodes. Noninvasive support was really beneficial in the myasthenic crisis with respiratory muscle weakness, whereas a shift to tracheal intubation was necessary when pulmonary infection and multiple atelectasis occurred. The new helmet interface for noninvasive positive pressure ventilation can represent a valuable means of respiratory support in the early phase of respiratory failure in older children.

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