• Critical care clinics · Oct 1986

    Review

    Massive transfusion.

    • R Rutledge, G F Sheldon, and M L Collins.
    • Department of Surgery, University of North Carolina, Chapel Hill School of Medicine.
    • Crit Care Clin. 1986 Oct 1; 2 (4): 791-805.

    AbstractMassive transfusion is a potentially serious problem associated with a number of complications, including changes in coagulation factor and platelet concentration, nonmechanical bleeding, hypothermia, pulmonary dysfunction, hypokalemia and hyperkalemia, hypocalcemia, hypomagnesemia, acidosis and alkalosis, immune suppression, blood transfusion reactions, and transmission of infectious diseases. The pathophysiology and management of massive transfusion are reviewed in this article.

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