• Dinesh Kumar Sahu, Vinca Kaul, and Reena Parampill.
• Department of Anaesthesiology and Advanced Pain Management, Jagjivanram Railway Hospital, Mumbai, India.
• Indian J Anaesth. 2011 Jul 1; 55 (4): 364-9.

BackgroundIn the present study, we compared isoflurane with sevoflurane in day care surgeries in order to determine the suitability of each agent for anaesthesia with Classical laryngeal mask airway (LMA).AimsThe aim of this study has been to compare isoflurane and sevoflurane as maintenance anaesthetic agents in day care surgeries with respect to intraoperative haemodynamics, recovery profile, time of first postoperative analgesia and pain score, adverse effects when used with classical LMA.Settings And DesignThis open - level, prospective randomized study was carried out on 60 patients who were admitted on a day care basis for elective short surgical procedures.MethodsThe patients were randomly assigned to one of the two study groups of 30 patients each. First group was maintained on isoflurane and second on sevoflurane as inhalational agent.Statistical AnalysisThe observations obtained in both the groups were recorded and tabulated. Statistical analysis was carried out using the Student t test, Chi-square test, Mann-Whitney test.ResultsEmergence from Sevoflurane was significantly quicker as compared to isoflurane. Sevoflurane group also showed earlier discharge time from the post anaesthesia care unit (PACU)-1 as compared to isoflurane group, but discharge time was same from the PACU-1. Isoflurane has more incidences of mild airway hyper reactivity when compared to sevoflurane.ConclusionsIt can be concluded that both isoflurane and sevoflurane are suitable for day care anaesthesia. Sevoflurane has little advantages of less airway hyper reactivity and quicker emergence and discharge from PACU-1.

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