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- K A Mobley, J G Wandless, and D Fell.
- Department of Anaesthesia, Leicester Royal Infirmary.
- Anaesthesia. 1991 Jun 1; 46 (6): 500-1.
AbstractSerum bupivacaine concentrations were measured in 12 children who underwent elective herniotomy and who received analgesia in the form of wound infiltration. Mean (SD) peak concentration was 0.36 (0.14) micrograms/ml and time to peak concentration was 14.6 (7.2) minutes after infiltration of 1.25 mg/kg of bupivacaine. These concentrations are lower than those associated with other local anaesthetic blocks and well below potentially toxic levels. Wound infiltration provides a simple, effective and safe method of providing postoperative analgesia for hernia repair in children.
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