• J Clin Pharm Ther · Dec 2007

    Case Reports

    4-Aminopyridine (fampridine) effectively treats amlodipine poisoning: a case report.

    • B Wilffert, R J Boskma, P H J van der Voort, D R A Uges, E N van Roon, and J R B J Brouwers.
    • Department of Pharmacotherapy and Pharmaceutical Care, GUIDE, University of Groningen, Groningen, The Netherlands. b.wilffert@znb.nl
    • J Clin Pharm Ther. 2007 Dec 1; 32 (6): 655-7.

    AbstractA case of a serious poisoning with the calcium entry blocker amlodipine is described, which was treated effectively with 4-aminopyridine. Calcium is suggested as general treatment of poisoning with calcium entry blockers in many guidelines. The use of intravenous 4-aminopyridine is theoretically useful to treat poisoning from calcium entry blockers and was demonstrated in this case report.

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