• Br J Anaesth · Oct 1998

    Randomized Controlled Trial Clinical Trial

    Remifentanil prevents an increase in intraocular pressure after succinylcholine and tracheal intubation.

    • R Alexander, R Hill, W J Lipham, K J Weatherwax, and H E el-Moalem.
    • Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA.
    • Br J Anaesth. 1998 Oct 1; 81 (4): 606-7.

    AbstractWe have studied changes in intraocular pressure (IOP) in 30 patients after succinylcholine (suxamethonium) and tracheal intubation following administration of propofol 2 mg kg-1 and either remifentanil 1 microgram kg-1 (group R) or saline (group S). IOP was measured before induction, before administration of succinylcholine and the study drug, before intubation and for every 1 min after intubation for 5 min. There was a significant decrease in IOP in group R compared with group S from the time of administration of the study drugs to the end of the study (P < 0.006).

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