• Ann. Thorac. Surg. · Jan 1998

    Case Reports

    Four multiple primary malignant neoplasms of the aerodigestive tract.

    • A Keshishian, F H Sarkar, G Kucyj, and J O Just-Viera.
    • Department of Pathology, St. Joseph Mercy Hospital, Pontiac, Michigan 48321, USA.
    • Ann. Thorac. Surg. 1998 Jan 1; 65 (1): 252-4.

    AbstractMultiple primary cancers of the head, neck, and upper aerodigestive tract have been documented in patients previously treated for oropharyngeal cancer. There generally is no causal relationship established between the different tumors. Two synchronous or metachronous cancers are common, three are unusual, and four are very unusual. We describe the treatment of a patient with tonsillar and synchronous esophageal and pulmonary cancers followed by a tongue cancer over a 6-year period.

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