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Case Reports
Intravenous cyclosporine therapy in the treatment of pyoderma gangrenosum secondary to Crohn's disease.
- J M Carp, E Onuma, K Das, and A B Gottlieb.
- Department of Dermatology, SUNY-Buffalo 14203, USA.
- Cutis. 1997 Sep 1; 60 (3): 135-8.
AbstractPyoderma gangrenosum is a destructive, ulcerative skin condition often associated with systemic illnesses such as inflammatory bowel disease, myeloproliferative disorders, and the inflammatory arthritides. We present a patient with long-standing pyoderma gangrenosum associated with Crohn's disease. Multiple deep leg ulcerations were unresponsive over the course of several years to treatment with azathioprine, systemic corticosteroids, 6-mercaptopurine, and dapsone. The patient was hospitalized and treated with a ten-day course of intravenous cyclosporine therapy followed by outpatient oral cyclosporine and showed significant improvement.
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