• Arq. Bras. Cardiol. · Jul 2008

    Case Reports

    Thiamin deficiency as a cause of reversible cor pulmonale.

    • Liana S Coelho, João C Hueb, Marcos F Minicucci, Paula S Azevedo, Sergio A R Paiva, and Leonardo A M Zornoff.
    • Departamento de Clínica Médica, Faculdade de Medicina de Botucatu, UNESP, Botucatu, SP, Brasil.
    • Arq. Bras. Cardiol. 2008 Jul 1; 91 (1): e7-9.

    AbstractThiamine deficiency may present four classic clinical forms: peripheral polyneuropathy, anorexia and muscular weakness (dry beriberi); high output heart failure with signs of congestion (wet beriberi); beriberi associated with shock (Shoshin beriberi) and Wernicke's encephalopathy. In this report we describe a picture that is suggestive of severe pulmonary hypertension and cor pulmonale, with jugular stasis, congestive hepatitis and generalized edema that reversed completely after the administration of thiamine.

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